a 96% satisfaction rate for sore feet worldwide - express delivery

The Feet In Systemic Lupus Erythematosus; Are We Underestimating Their Involvement And Functional Impact?

by MASS4D® Prescription Orthotics May 20, 2018


The main objective of this cross-sectional study was to comprehensively evaluate biomechanical and musculoskeletal ultrasound (US) abnormalities in a population of systemic lupus erythematosus (SLE) patients as compared with controls, both with and without foot complaints.

The secondary objective was to assess the relationship between biomechanical and US abnormalities and SLE activity, and the presence of auto-antibodies in these patients.

Fifty-four consecutive female patients with SLE (with and without foot pain) and sixty female controls (30 with foot pain and 30 without foot pain) were recruited.

Data on demographics, SLE duration and current treatment, presence of arthritis at onset or during disease course, disease-related auto-antibodies, rheumatoid factor (RF), and anti-citrullinated peptide antibodies (ACPAs) were collected from the Autoimmune Systemic Rheumatic Diseases Electronic Registry of the Department of Rheumatology.

Offer your Patients a Custom Calibrated Insole with a 98% Patient Satisfaction Rate     know more

All SLE patients and controls underwent a complete podiatric investigation by a Doctor in Podiatric Medicine (DPM).

Musculoskeletal US assessment consisted of a systematic longitudinal and transverse multiplanar examination.

SLE activity was assessed by the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI).

Foot pain was found to be predominantly inflammatory or mixed in SLE patients, possibly due to the inflammatory nature of joint involvement in this disease whereas foot pain was observed to be mostly mechanical in controls.

MTP joints were the most common location for pain in SLE patients and for B-mode synovitis on US in total and painful feet of SLE patients.

There were no significant differences in these variables between SLE patients and controls and between painful and painless feet in SLE patients.

A strong association between having SLE and the presence of tibiotalar B-mode US synovitis as well as between having foot pain in SLE patients and again the presence of tibiotalar B-mode US synovitis and a limited mobility of this joint.

SLE patients showed more biomechanical and US feet abnormalities than controls without SLE.

Biomechanical and ultrasound feet abnormalities were not captured by standardised assessment of disease activity.

Copyright 2018 MASS4D® All rights reserved.

Offer your Patients a Custom Calibrated Insole with a 98% Patient Satisfaction Rate     know more


  1. Morales-Lozano, R., Martínez-Barrio, J., González-Fernández, M. L., López-Longo, F. J., Ovalles-Bonilla, J. G., Valor, L., Janta, I., Nieto, J. C., Hernández-Flórez, D., González, C. M., Monteagudo, I., Garrido, J., Carreño, L., Naredo, E. (2016) The Feet In Systemic Lupus Erythematosus; Are We Underestimating Their Involvement And Functional Impact? Clinical and Experimental Rheumatology: 2016, Vol. 34, pp. 609-617

Also in Clinicians Blog

Prevention of Diabetic Foot Complications

by MASS4D® Prescription Orthotics November 13, 2018

This paper aimed to discuss the importance of prevention and the authors’ protocol for prevention – in the form of education and foot screening – and to review the existing evidence in the literature regarding the effectiveness of the preventive approach.

Read More

Foot Disorders, Foot Posture, and Foot Function: The Framingham Foot Study

by MASS4D® Prescription Orthotics November 04, 2018

The purpose of this study was to assess the relation between foot disorders, and foot posture and function in a population-based sample of adults.

Read More

Potential for foot dysfunction and plantar fasciitis according to the shape of the foot arch in young adults

by MASS4D® Prescription Orthotics October 30, 2018

This study aimed to verify the potential for functional abnormality of the foot and plantar fasciitis among people with flat feet.

Read More